From Long Island:

Take the Grand Central Parkway West to the Brooklyn, Queens Expressway and exit on Tillary Street.  Make a right turn on Flatbush Avenue Extension and go over the Manhattan Bridge.  Exit bridge at Canal Street going West.  Make a right turn on Elizabeth Street.  Take Elizabeth Street to Houston Street.  Proceed on Houston Street to Ridge Street and make a right. Castellano is on the right hand side of the street in the middle of the block.